Global Treatment Options
The current treatment regime for localised prostate cancer is active Surveillance, though this is mostly followed for low-risk cases. However the more specific treatment advised for confirmed and aggressive cases includes Surgery — radical prostatectomy, and Radiation therapy using external beam or brachytherapy.
But, there are a host of new generation treatments currently available at modern settings for advanced or metastatic cancer. These options include Hormone Therapy (ADT), a first-line treatment for advanced disease, Androgen Receptor Inhibitors, Chemotherapy using drugs like Docetaxel, and Cabazitaxel.
The new generation treatments include targeted Therapy, Immunotherapy ( approved only in some countries), and Radioligand Therapy, which are promising for metastatic castration-resistant prostate cancer (mCRPC).
According to a senior professor at US’s MD Anderson Cancer Centre, who spoke to The New Indian Express seeking confidentiality, the diagnoses like Biden’s diagnosis is serious, but not hopeless.
“While his case is unusual due to his age and the cancer’s spread, modern treatments often work well—especially if the cancer responds to hormone therapy. The case also highlights the ongoing debate about who should get screened for prostate cancer and when,” he said.
Biden is exploring multiple treatment options, including hormone therapy, which reduces testosterone (a hormone that fuels the cancer.
Most patients with advanced prostate cancer respond well to initial treatments, sometimes for several years. In some cases, chemotherapy or radiation is added.
About 37% of patients with advanced prostate cancer live at least five years after diagnosis.
Prostate cancer remains a major global health concern, especially in aging populations. Advances in imaging, genomic testing, and personalised treatments have significantly improved outcomes.
However, Biden’s case brings back the importance of screening and early detection.
Some doctors say it’s unusual for someone under regular medical care to be diagnosed at such an advanced stage. However, aggressive cancers can grow and spread quickly in rare cases. Early detection and equitable access to advanced diagnostics and therapies are critical to reducing global disparities in care.